Gamal Moustafa

Assoc. Prof. Dr. GAMAL MOUSTAFA

Faculty of Pharmacy

Telephone number +90 392 671 11 11
Extension 2671
Office No. ST252
Other information

CURRICULUM VITAE

Education
  • Ohio State University, Davis Heart & Lung Research Institute, USA MEDICINE (Professional Doctorate, 2010)
  • Zagazig University, Egypt PHARMACY (PhD, 2004)
  • Assiut University EGYPT PHARMACY (Master, 1999)
  • Mansoura University, Egypt PHARMACY (Undergraduate, 1990)
Publications

Articles published in peer reviewed international journals (SCI,SSCI,Arts and Humanities)

  • Potentiality of raloxifene loaded melittin functionalized lipidic nanovesicles against pancreatic cancer cells.Usama A. Fahmy, Shaimaa M. Badr-Eldin, Hibah M. Aldawsari, Nabil A.Alhakamy, Osama A. A. Ahmed, Mohamed F. Radwan, Basma G. Eid, ShabanR. M. Sayed, Gamal A. El Sherbiny & Walaa Abualsunun. DRUG DELIVERY2022, VOL. 29, NO. 1, 1863–1877https://doi.org/10.1080/10717544.2022.2072544 - 2022
  • Potentiality of raloxifene loaded melittin functionalized lipidic nanovesicles against pancreatic cancer cells - 2022
  • Thymoquinone Protects against cigarette smoke extract-induced vascular dysfunction through inhibition of the RhoA/Rhokinase singling pathway. Gamal A. Moustafa, Mohamed A. El-Mahdy, Raed S. Ismail, Ahmed M. Mansour. The FASEB Journal, Volume 34, Issue S1, First published:19 April 2020. - 2020
  • Quercitrin, a natural flavonoid glycoside, protects against cisplatin-induced injury in rats without hindering cisplatin beneficial cytotoxic activityAuthor(s): Arafa, EA (Arafa, Elshaimaa A.); Mohamed, W (Mohamed, Wafaa); Shehata, B (Shehata, Basim); Hassan, H (Hassan, Hossam); Raslan, M (Raslan,Mai); Elsherbiny, G (Elsherbiny, Gamal); Elgendy, A (Elgendy, Abelnasser)Source: FASEB JOURNAL Meeting Abstract: 819.3 Volume: 31 Supplement: 1 Published: APR 2017. - 2017
  • Abd-Elbaset M, Arafa EA, El Sherbiny GA, Abdel-Bakky MS, Elgendy AN. Thymoquinone mitigate ischemia reperfusion-induced liver injury in rats: a pivotal role of nitric oxide signaling pathway. NaunynSchmiedebergs Arch Pharmacol.2017 Jan; 390(1):69-76. - 2017
  • El-Bahrawy AH, Tarhuni A, Kim H, Subramaniam V, Benslimane I, Elmageed ZY, Okpechi SC, Ghonim MA, Hemeida RA, Abo-Yousef AM, El-Sherbiny GA, Abdel-Raheem IT, Kim J, Naura AS, Boulares AH. ApoE deficiency promotes colon inflammation and enhances the inflammatory potential of oxidized-LDL and TNF-α in primary colon epithelial cells. Biosci Rep.2016 Nov 17; 36 (6)1-11. - 2016
  • Omar HA, Mohamed WR, Arafa el-SA, Shehata BA, El Sherbiny GA, Arab HH, Elgendy AN. Hesperidin alleviates cisplatin-induced hepatotoxicity in rats without inhibiting its antitumor activity. Pharmacol Rep.2016 Apr; 68(2):349-56. - 2016
  • Abd-Elbaset M, Arafa EA, El Sherbiny GA, Abdel-Bakky MS, Elgendy Quercetin modulates iNOS, eNOS and NOSTRIN expressions and attenuates oxidative stress in warm hepatic ischemia-reperfusion injury in rats. Beni-Suef University Journal of Basic and Applied Sciences 4 (2015) 246–255 - 2015
  • Wafaa R. Mohamed, El-Shaimaa A. Arafa, Basim A. Shehata, Gamal A. El Sherbiny and Abdel Nasser A.M. Elgendy. Beneficial Effects of Hesperidin against Cisplatin-Induced Nephrotoxicity and Oxidative Damage. British Journal of Pharmacology and Toxicology 6(3): 56-63, 2015 - 2015
  • Wafaa R. Mohamed, El-Shaimaa A. Arafa, Basim A. Shehata, Gamal A. El Sherbiny and Abdel Nasser A.M. Elgendy. Beneficial Effects of Hesperidin against Cisplatin-Induced Nephrotoxicity and Oxidative Damage. British Journal of Pharmacology and Toxicology 6(3): 56-63, 2015 - 2015
  • Cigarette smoke extract causes endothelial nitric oxide synthase dysfunction through S-glutathionylationAuthor(s): Abdelghany, TM (Abdelghany, Tamer M.); Hemann, C (Hemann, Craig); El-Sherbiny, GA (El-Sherbiny, Gamal A.); ElMahdy, MA (El-Mahdy, MohamedA.); Zweier, JL (Zweier, Jay L.) Source: FASEB JOURNAL Meeting Abstract: 890.11 Volume: 27 Published: APR 2013. - 2014
  • Thymoquinone protects against myocardial ischemia-reperfusion injury via modulation of oxidant generation and nuclear factor-kappaB-mediatedresponsesAuthor(s): El-Mandy, M (El-Mandy, Mohamed); Ismail, R (Ismail, Raed); Hemann, C (Hemann, Craig); El-Sherbiny, G (El-Sherbiny, Gamal); Abdelghany, T(Abdelghany, Tamer); Helal, G (Helal, Gouda); Weier, J (Weier, Jay)Source: FASEB JOURNAL Meeting Abstract: 1080.1 Volume: 28 Issue: 1 Supplement: S Published: APR 2014. - 2014
  • Ramadan A. M. Hemeida, Ihab T. Abdel-Raheem, Gamal A. El-Sherbiny, El-ShaimaaA.Arafa, Abdel-Gawad S. Candesartan modulates the antioxidant effect of silymarin against CCl4-induced liver injury in rats. Free Radicals and Antioxidants Vol.4 / Issue 1 / Jan–Jun, 2014. - 2014
  • Modulation of mdr-1 Expression and Activity by Verapamil and Resveratrol Potentiates the Cytotoxicity of Docetaxel and Doxorubicin in Solid TumorCell LinesAuthor(s): El-Moselhy, MAM (El-Moselhy, Mohamed Ahmed Mohamed); ElSherbiny, GA (El-Sherbiny, Gamal Ahmed); Abd Abdel-Latif, HAT (Abd Abdel-Latif,Hekma Abdel-Tawab); Al-Abd, AM (Al-Abd, Ahmed Mohamed); Nofal, SM (Nofal, Salwa Mohamed); El-Eraky, WI (El-Eraky, Wafaa Ibraheem)Source: FASEB JOURNAL Volume: 26 Published: APR 2012. - 2012
  • Potential Proteomic Biomarkers of Secondhand Smoking-Induced Cardiovascular DiseaseAuthor(s): Zweier, JL (Zweier, Jay L.); Tewari, AK (Tewari, Arun K.); El-Mahdy, MA (El-Mahdy, Mohamed A.); Abdelghany, TM (Abdelghany, Tamer M.); Hemann,C (Hemann, Craig); El-Sherbiny, GA (El-Sherbiny, Gamal A.)Source: FASEB JOURNAL Volume: 26 Published: APR 2012. - 2012
  • Antinociceptive Effect Of Whey Protein And Its Fractions In Swiss Albino Mice. eliwa, Hesham. A; El-Denshary, Ezzedin S.; nada, Somaia A.; elsherbini, gamal; IJPRBS, 2012; Volume 1(6):355-381. - 2012
  • Al-Abd AM, Mahmoud AM, El-Sherbiny GA, El-Moselhy MA, Nofal SM, El-Latif HA, El-Eraky WI, El-Shemy HA. Resveratrol enhances the cytotoxic profile of docetaxel and doxorubicin in solid tumour cell lines in vitro. Cell Prolif.2011 Dec;44(6):591-601. - 2011
  • Resveratrol potentiates the cytotoxic profile of docetaxel and doxorubicin via inhibiting the activity and expression of pglycoprotein moleculesAuthor(s): Al-Abd, AM (Al-Abd, Ahmed M.); Mahmoud, AM (Mahmoud, Ali M.); Nofal, SM (Nofal, Salwa M.); El-Sherbiny, GA (El-Sherbiny, Gamal A.); El-Moselhy,MA (El-Moselhy, Mohammed A.); AbdelTawab, HAA (Abdel-Tawab, Hekma A. Ahmed); El-Eraky, WI (El-Eraky, Wafaa I.); El-Shemy, HA (El-Shemy, Hany A.)Source: CANCER RESEARCH Meeting Abstract: 1698 Volume: 71 DOI: 10.1158/1538-7445.AM2011-1698 Supplement: 8 Published: APR 15 2011 - 2011
  • Adverse and drug interaction of drinking licorice Author(s): El Koussi, A (El Koussi, A); Mongoura, S (Mongoura, S); Rahma, HA (Rahma, HA); El Sherbiny, G (El Sherbiny, G); Abu Elwafa, A (Abu Elwafa, A) NAUNYNSCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY Meeting Abstract: P5167 Volume: 358 Issue: 1 Pages: R500R500 Supplement:2 Published: 1998. - 1998

Other Publications

  • Impact of COVID-19 Lockdown on Sleep Quality of Pharmacy Students in UiTM Puncak Alam - 2021

Articles published in other peer reviewed international journals

  • Beneficial Effects of Hesperidin against Cisplatin-Induced Nephrotoxicity and Oxidative. . British Journal of Pharmacology - 2015
  • Afaf A. Ain-Shoka, Mostafa E. El-Sayed, Souty M. Sharkawi, Gamal Ahmed El-Sherbiny. Prophylactic Role of Echinacea, Green Tea and Boswellia Extracts in Pyloric Ligation-Induced Gastric Ulcer in Rats. British Journal of Pharmacology and Toxicology 5 (3), 197-204, 2012. - 2012
  • W.R. Mohamed, G.A. El Sherbiny, H.F. Zaki and M.E. El Sayed. Modulation of the Antidiabetic Effect of Glimepiride by Diazepam in Diabetic Rats. British Journal of Pharmacology and Toxicology 3(5): 190-196, 2012. - 2012

Articles published in National journals

  • Sayed M. Mizar, Hany A. Omar, Mohammed A, G. A. Elsherbiny and El-moselhy. Nebivolol and chrysin protect the liver against ischemia/reperfusion-induced injury in rats. Beni-Suef University journal of basic and applied science 4(2015) 86-92. - 2015
  • Mahmoud, H. M., H. F. Zaki, G. A. Elsherbiny, and H. A. Abdel-Latif, "Modulatory role of chelating agents in diet induced hypercholesterolemia in rats", Bulletin of Faculty of Pharmacy, Cairo University, vol. 52, pp. 27-35, 2014. - 2014
  • Mahmoud, H. M., H. F. Zaki, G. A. Elsherbiny, and H. A. Abdel-Latif. Effects of Simvastatin and Vitamin E on Diet Induced Hypercholesterolemia in Rats. British Journal of Pharmacology and Toxicology 5(1): 16-25, 2014. - 2014
  • Marwa M.A. Khalaf, Gamal A. El Sherbiny, Hekma A. AbdEllatif, Afaf A. Ain-shoka, Mostafa E. El Sayed. Comparative Effects of Glimepiride, Vanadyl Sulfate and Their Combination on Hypoglycemic Parameters and Oxidative Stress in Rats. British Journal of Pharmacology and Toxicology 3(6): 278-288, 2012. - 2012
  • El-Sherbiny GA, Protective Effect of Boswellia Serrata extract against Caerulein-induced Acute Pancreatitis in Rats. MJPS VOL. 25(1) 2009, 12-22. - 2009
  • induced Hepatotoxicity in vitro; Modulatory Role of Inducible NOS Inhibitors Versus Non – Inducible Ones" Zag. Uni. Med. J.SPECIAL ISSUE. 22-25 March, 2009; 230-262. - 2009
  • Abdel Raheem, El-Sherbiny GA,Taye A. Green Tea Ameliorates Renal Oxidative Damage induced by Gentamicin in Rats." MJPS VOL. 25(1) 2009, 1-11. - 2009
  • bdel El Bakry AE, El-Sherbiny GA. Efficacy of Iron Chelator in the Amelioration the Adverse Effect of Iron-overload in Rats. Zag. Uni. Med. J. SPECIAL ISSUE. 22-25 March, 2009; 263-273. - 2009
  • Shehata BA, El-Sherbiny GA, El-Sayed NS, Zaki HF, Abdel-Tatif. “Ischemia-Reperfusion liver injury in rats; can herbal medicines really Protect?”. MJPS VOL. 24(8) 2008, 199-213. - 2008
  • aye A, El-Moselhy MA, Morsy MA, El-Sherbiny GA. Hepatoprotective effect of Nicorandil Against Carbon Tetrachloride-Induced Hepatotoxicity in Rats. "El-MMINIA MED., BULL., VOL. 19, NO. 1, JAN., 2008,312-323 - 2008
  • El-Sherbiny GA, El-Moselhy MA, Morsy MA, Fouad MA. Antidiabetic effect of Portulaca Oleracea extract, alone and plus gliclazide , on streptozotocin-nicotinamide-induced type 2 diabetes in rats.” El-MMINIA MED., BULL., VOL.16, NO.2 JUN, 2005,264-270. - 2008
  • El-Sherbiny GA, FahmeyA, Ghareb S, Hemeida R. Silymarin and Gliclazide Delay the Incidence of Diabetes in Normal and Cirrhotic Rats”. Al-Azhar Assiut Medical Journal,1,3: (1-24),2003. - 2003
  • El-Sherbiny GA, FahmeyA, Ghareb S, Hemeida R. “Aloes and Silymarin Protect Rats Against CCL4-Induced Cirrhosis”. Al-Azhar Assiut Medical Journal ,1,2:(91-110),2003. - 2003
Thesis Supervision

Master Thesis Supervised

  • Master Candidate: Sayed Mezar."Pharmacological study of the possible protective effects of B-blockers and statins in experimentally-induced liver injury" Department of Pharmacology and Toxicology, Faculty of Pharmacy, Beni-Suef University, Egypt. - 2011
  • Master Candidate: Mohamsd A. Farhat. "Pharmacological study of possible protective effect of certain antioxidants in experimentally induced liver injury in rats" Department of Pharmacology and Toxicology, Faculty of Pharmacy, Beni-Suef University, Egypt. - 2009
  • Master Candidate: Heba Mohesen." Pharmacological study of the effects of certain chelating agents and some hypocholesterolemic drugs in hypercholesterolemic rats" Department of Pharmacology and Toxicology, Faculty of Pharmacy, Beni-Suef University, Egypt. - 2008
  • Master Candidate: Mai AbdAlah M.Taha. " Pharmacological Study of the effect of a statin and some antioxidants on myocardial infarction in hypercholestermic rats" Department of Pharmacology and Toxicology, Faculty of Pharmacy, Beni-Suef University, Egypt. - 2007
  • Master Candidate: Wafaa Rabea: "Pharmacological study of the possible interactions between certain antidiabetics and antianxity drugs in experimentally-induced diabetic animals" Department of Pharmacology and Toxicology, Faculty of Pharmacy, Beni-Suef University, Egypt. - 2006
  • Master Candidate: Wafaa Rabea: "Pharmacological study of the possible interactions between certain antidiabetics and antianxity drugs in experimentally-induced diabetic animals" Department of Pharmacology and Toxicology, Faculty of Pharmacy, Beni-Suef University, Egypt. - 2006
  • Master Candidate: Mohamed Ragab. “Pharmacological Study of the Possible Protective Effects of Some Citrus Fruits Peel Extracts Against Experimentally Induced Hepatotoxicity in Rats”. Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Egypt. - 2006
  • Master Candidate: Rania AbdAlah M. Gad. "Pharmacological study of the possible protective effect of some citrus fruits peel extract against experimentally induced hepatotoxicity in rats" Department of Pharmacology and Toxicology, Faculty of Pharmacy, Beni-Suef University, Egypt. - 2005
  • Master Candidate: Hisham A. Helmy."Antinocicepative effect of whey protein and its fractions in Swiss Albino mice" Department of Pharmacology and Toxicology, Faculty of Pharmacy, Beni-Suef University, Egypt. - 2005

Doctorate Thesis Supervised

  • Ph.D Candidate: Ali Ibrahem. "High fat diet-coupled systemic inflammation as a determinant of colon cancer"" Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Egypt. - 2010
  • Ph.D Candidate: Amany Abd-Elkhalek. "Possible protective effect of some vasodilators and certain antioxidant agent against experimentally-induced nepherotoxicity in rats” Department of Pharmacology and Toxicology, Faculty of Pharmacy, Beni-Suef University, Egypt. - 2009
  • Ph.D Candidate: Wafaa Rabea. "Pharmacological study on the possible protective effects of certain antioxidants against cisplatin-induced hepatotoicity and nephrotoxicity" Department of Pharmacology and Toxicology, Faculty of Pharmacy, Beni-Suef University, Egypt. - 2009
  • Ph.D Candidate: Abd El-Gwad Shalkamy. "Effect of renin-angiotensin system inhibitors and sylimarin on the hepatic fibrosis development in rats" Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-azhar University, Egypt. - 2008
  • Ph.D Candidate: Ahmed Al Abd."The effect of p-glycoprotien inhibitors on the pharmacological profile of some anticancer drugs" Department of Pharmacology and Toxicology, Faculty of Pharmacy, Beni-Suef University, Egypt. - 2006
  • Ph.D Candidate: Basem Anwar Shehata. “Pharmacological Study of the Possible Protective Effects of Some Antioxidants against Experimentally-Induced Hepatotoxicity in Rats”. Department of Pharmacology and Toxicology, Faculty of Pharmacy, Beni-Suef University, Egypt - 2005
  • Ph.D Candidate: Marwa Mohamed Khalaf. “Pharmacological Study of the Possible Interaction Between AntiDiabetics and Certain Anti-Anxiety Drugs. Experimentally Induced Diabetic Animals”. Department of Pharmacology and Toxicology, Faculty of Pharmacy, Beni-Suef University, Egypt. - 2005
Projects
  • EFFECT OF CIGGERET SMOOKING ON CARDIOVASCULAR SYSTEM
  • Diabetes control in case of hepatic insufficiency; experimental and clinical study
  • "Possible interactions between liquorice and some antihypertensive agents"
Awards
  • The best research proposal from Benı suıf unıversıty Egypt 2005
Research Areas
  • Molecular mechanisms of anticancer drugs. Molecular pharmacology as a basis for drugs development. Molecular pharmacology as a basis for cardiovascular drugs development. Oxidative stress and antioxidants implication in the pathophysiology of many clinical disorders.